Table 1. Comparison of the clonal complex distribution of the study isolates and all English, Welsh and Northern Irish serogroup B invasive meningococcal disease isolates for the epidemiological year 2007/8.
Clonal complex | Proportion of isolates (number) | |
Study (80) | 2007/8 (539) | |
11 | 2.5% (2) | 1.1% (6) |
18 | 1.3% (1) | 1.7% (9) |
32 | 7.5% (6) | 5.9% (32) |
35 | 1.3% (1) | 1.5% (8) |
60 | 3.8% (3) | 2.0% (11) |
103 | 1.3% (1) | 0.2% (1) |
162 | 5.0% (4) | 1.9% (10) |
213 | 6.3% (5) | 9.5% (51) |
269 | 27.5% (22) | 33.0% (178) |
461 | 2.5% (2) | 2.2% (12) |
1157 | 3.8% (3) | 0.4% (2) |
41/44 | 26.3% (21) | 31.5% (170) |
UA | 11.3% (9) | 7.2% (39) |
other | n/a | 1.9% (10) |
Isolates used in the study were selected to represent the diversity and distribution (in terms of clonal complex) of all English, Welsh and Northern Irish invasive MenB isolates from 2007/8. Note that a proportion of the predominant CCs (cc269 and cc41/44) were forfeited to include lesser CCs. Other variations were due to the limited availability of multilocus sequence typed isolates with accessible clinical specimens. UA = unassigned STs. n/a = not applicable.