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. 2013 Sep 30;8(9):e76210. doi: 10.1371/journal.pone.0076210

Figure 4. Quercetin reduces calcium accrual in Mgp-/- mice.

Figure 4

A-B, Total calcium in aortic tissue from 5 week old untreated Mgp-/- mice (N=8) or Mgp-/- mice treated with 0.02% w/w dietary quercetin for 2 weeks after weaning (A; N=16) or for 5 weeks from birth through weaning (B; N=9). Heterzygous (Mgp+/-) mice served as control (N=6). C, Von Kossa stain for calcified matrix deposition in aortic tissue from Mgp+/-, untreated Mgp-/-, and quercetin-treated Mgp-/- animals. Sections from 2 representative animals are shown. Arrows denote chondrogenic metaplasia. Scale = 50 µm.