Table 2. In vitro left ventricular function and systolic blood pressure.
SHAM (n= 6) | SHAM-S (n= 4) | MI (n= 6) | MI -S (n= 5) | p MI | p S | p MIxS | |
---|---|---|---|---|---|---|---|
+ dp/dt max (mmHg/s) | 4041 ± 1111 | 4594 ± 449 | 2437 ± 931 | 2150 ± 736 | <0.001 | 0.739 | 0.298 |
- dp/dt max (mmHg/s) | 2083 ± 385 | 2344 ± 359 | 1354 ± 490 | 1275 ± 311 | <0.001 | 0.615 | 0.350 |
Systolic blood pressure (mmHg)# | 130 ± 21.2 | 115 ± 20.3 | 119 ± 15.8 | 126 ± 17.9 | 0.898 | 0.400 | 0.052 |
S: spironolactone; MI: myocardial infarction; + dp/dt max: maximum rate of ventricular pressure rise; - dp/dt max: decreased maximum rate of ventricular pressure rise. # (SHAM=9; SHAM-S=9; MI=15; MI-S=15).