Table 3. Morphological data.
| SHAM (n= 9) | SHAM-S (n= 9) | MI (n= 16) | MI -S (n= 15) | p MI | p S | p MIxS | |
|---|---|---|---|---|---|---|---|
| LVW/BW (g/mg)* | 1.81 ± 0.21 | 1.54 ± 0.40 | 2.04 ± 0.54•,ƒ | 1.88 ± 0.51 | 0.038 | 0.115 | 0.695 |
| RVW/BW (g/mg)* | 0.41 ± 0.11 | 0.34 ± 0.11 | 0.69 ± 0.33 | 0.52 ± 0.20 | 0.001 | 0.084 | 0.464 |
| MHPO (mg/g)# | 2.95 ± 0.21 | 3.42 ± 0.45 | 5.67 ± 0.70•,ƒ | 4.17 ± 0.83 | <0.001 | 0.121 | 0.008 |
| CSA (µm2)** | 315 ± 56 | 311 ± 67 | 483 ± 63•,ƒ | 370 ± 56 | <0.001 | 0.016 | 0.025 |
S: spironolactone; MI: myocardial infarction; BW: body weight; LVW: left ventricular weight; RVW: right ventricular weight; MHPO: myocardial hydroxyproline concentration; CSA: cross-sectional area. * data normalized for statistical analysis.
#
(SHAM=4; SHAM-S=5; MI=4; MI-S=4.)
**
(SHAM=8; SHAM-S=7; MI=6; MI-S=8.)
When interactions were observed, symbols show the significant differences (• MI≠MI-S and ƒ MI≠SHAM)