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. 2013 Jul 4;6(3):689–695. doi: 10.3892/etm.2013.1203

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Copyright © 2013, Spandidos Publications

This is an open-access article licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported License. The article may be redistributed, reproduced, and reused for non-commercial purposes, provided the original source is properly cited.

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Plasma insulin levels in Zucker diabetic fatty (ZDF) and lean ZDF rats treated with 125 or 250 mg/kg anthocyanin (ANC) or 1% carboxymethylcellulose (CMC) for 5 weeks. Plasma insulin levels at week 0 were significantly higher in the ZDF rats than in their lean littermates (P<0.001). The insulin secretion in the 250 mg/kg ANC-treated ZDF rats at week 5 was 27% higher than that in the CMC-treated ZDF rats. The results are shown as the mean ± standard deviation (n=3–5 rats/group). ^*P<0.001.