Table 1. Overexpression of Morgue results in lethality.
| parents | offspring | ||||
| female | male | + | balancer | +/balancer ratio | ratio if fully viable |
| da-Gal4/da-Gal4 | da-Gal4/TM3 | 176 | 162 | 1.09 | 1.00 |
| da-Gal4/TM3 | da-Gal4/TM3 | 310 | 529 | 0.59 | 0.50 |
| da-Gal4, UAS-GFP/TM3 | da-Gal4, UAS-GFP/TM3 | 530 | 1191 | 0.45 | 0.50 |
| da-Gal4, UAS-morgue1/TM3 | da-Gal4, UAS-morgue1/TM3 | 0 | 1278 | 0.00 | 0.50 |
| da-Gal4, UAS-morgue2/TM3 | da-Gal4, UAS-morgue2/TM3 | 0 | 975 | 0.00 | 0.50 |
| da-Gal4/da-Gal4 | da-Gal4,UAS-morgue1/TM3 | 50 | 238 | 0.21 | 1.00 |
| da-Gal4/da-Gal4 | da-Gal4,UAS-morgue2/TM3 | 0 | 183 | 0.000 | 1.00 |
| da-Gal4, UAS-morgue1/TM6B | UAS-morgue1/UAS-morgue1 | 1 | 83 | 0.012 | 1.00 |
| da-Gal4, UAS-morgue1/TM3 | UAS-morgue1/UAS-morgue1 | 1 | 180 | 0.006 | 1.00 |
| da-Gal4, UAS-morgue2/TM3 | UAS-morgue1/UAS-morgue1 | 32 | 238 | 0.13 | 1.00 |
Effects of widespread Morgue expression on fly viability. Counts of heterozygote (balancer) and homozygote non-balancer (+) progeny derived from genetic crosses where P[da-Gal4] was used to drive expression of P[UAS-GFP] or P[UAS-Morgue]. Homozygous P[da-Gal4] or P[da-Gal4],P[UAS-GFP] flies are viable while P[da-Gal4],P[UAS-Morgue] homozygotes are completely lethal. Flies containing two copies of P[da-Gal4] and one copy of P[UAS-Morgue] or vice versa exhibit either complete or significant lethality. UAS-morgue1 and UAS-morgue2 represent independent insertions of P[UAS-Morgue].