Table 2. Overexpresion of Morgue deletion (MorgueΔ) mutants exhibit variable viability.
| UAS-linked gene | + | balancer | +/balancer ratio | ratio if fully viable |
| GFP | 530 | 1191 | 44.5% | 50% |
| Morgue (1) | 0 | 1278 | 0% | 50% |
| Morgue (2) | 0 | 975 | 0% | 50% |
| MorgueΔZF (1) | 568 | 1866 | 30.4% | 50% |
| MorgueΔZF (2) | 385 | 1614 | 23.9% | 50% |
| MorgueΔFB (1) | 43 | 1587 | 2.7% | 50% |
| MorgueΔFB (2) | 0 | 471 | 0% | 25% |
| MorgueΔUEV (1) | 408 | 1591 | 25.6% | 50% |
| MorgueΔUEV (2) | 593 | 1509 | 39.3% | 50% |
| MorgueΔ (FB+UEV) | 651 | 1750 | 37.2% | 50% |
| MorgueΔ (ZF+FB) (1) | 82 | 484 | 16.9% | 25% |
| MorgueΔ (ZF+FB) (2) | 55 | 296 | 18.6% | 25% |
Effects of widespread expression of Morgue deletion mutants on fly viability. Counts of homozygous non-balancer (+) and heterozygote balancer progeny derived from genetic crosses where P[da-Gal4] was used to drive expression of P[UAS-GFP] or various P[UAS-MorgueΔ] strains. Homozygote (non-balancer) and heterozygote (with either a TM3 or both a CyO and a TM3 balancer) progeny derived from: P[da-Gal4], P[UAS-MorgueΔ]/TM3, P[da-Gal4], P[UAS-GFP]/TM3, or P[UAS-MorgueΔ]/CyO, P[da-Gal4]/TM3 parent flies were counted. Expression of MorgueΔZF, MorgueΔFB, MorgueΔUEV, and MorgueΔZF-FB resulted in reduced Morgue-induced lethality. In contrast, removal of the F box alone retained near complete Morgue-induced lethality. Note that if the homozygotes are fully viable, the expected percentage of viable flies is either 50% or 25% depending on whether one or two balancer chromosomes are present.