Figure 2.

Cardiomyocyte apoptosis observed by TUNEL staining. (A) Young control group, the young rat group have negligible dark nuclei of apoptotic myocardial cells; (B) aging rat group, which has the largest amount of apoptotic (dark) myocardial cells; (C) low-dose atorvastatin group, apoptosis in myocardial cells reduced compared with the aging control; (D) high-dose atorvastatin group, the apoptosis was lower than low-dose group. TUNEL, terminal deoxynucleotidyl transferase-mediated dUTP-biotin nick end labeling.