Table 3. Pharmaceutical substances with decreasing originator market share (2001–2011) and no generic counterpart on market.

PERU	COLOMBIA	ECUADOR	URUGUAY	PHILIPPINES	VENEZUELA	SOUTH AFRICA	MEXICO	JORDAN	UNITED STATES
Acetylsalicylic acid/ chlorphanamine/ pseudoephedrine	Caffeine/diphen -hydramine/ ergotamine	Chlorphenamine/ salicylic acid	Diphenhydra- mine/guaifenesin	Betamethasone/ dexchlorphenir-amine	Betamethasone /dexchlorphenir-amine	Rofecoxib	Pseudo-ephedrine/ triprolidine	Amitriptyline	Celecoxib
Dextromethorphan/ diphenhydramine	Fluphenazine/ nortriptylline	Diphenhydramine	Diphenhydra-mine/ paracetamol/ phenylpropanol-amine	Betamethasone	Rofecoxib		Acetyl-salicylic acid/ Chlorphen-amine/ Pseudoephe-drine	Biperiden	Rofecoxib
	Metildigoxin	Dextromethorphan/ diphenhydramine		Betamethasone/ chlorphenamine	Celecoxib		Dexbrom-pheniramine/ pseudephed-rine	Clobutinol/ orciprenaline
	Bromelains/dihydrocholic acid/ dimeticone/ metoclopramide/ pancreatin	Chlorphenamine/ phenylephrine/salicylamide		Diphenhydra-mine/guaifenesin	Ephedrine/ hydroxyzine/ theophylline			Clonazepam
	Hydrochlorthia- zide/propranolol	Acetylsalicylic acid/caffeine/		Atropine diphenoxylate	Lorazepam			Flupentixol
		Rofecoxib		Guaifenesin/ terbutaline	Metamizole sodium/ scopalamine butyl hydroxide			Clopamide/ dihydro- ertocristine/ reserpine
		Calcium/copper/ dexpanthenol/ iron/magnesium/ manganese/ molybdenum/ multivitamins/ phosphorus/ potassium/ vitamin E/zinc		Ketotifen	Triazolam			Hydroxyzine

Legend: Ingredients separated by backslash (/) are part of the same combination.