Table 1. TRIM5α and MHC Genotypes.

RM #	TRIM5α genotype	Susceptibility to infection	MHC genotypes			# SIVsmE660 challenges
			A01	B08	B17	Low-dose High-dose
Group 1 (vaccine 8 yrs prior, followed by low-dose repeated challenge)
RJi-6	TFP/ Q	moderate	–	–	–	17	1
ROI-3	TFP/ TFP	restrictive	–	–	–	5	0
RQh-6	Q/ CYPA	moderate	–	–	–	17	1
RUu-3	TFP/ TFP	restrictive	–	+	–	4	0
Group 2 (vaccine 15 mos prior, followed by low-dose repeated challenges)
RAn-8	Q/ Q	high	–	–	–	6	0
RBm-8	TFP/ Q	moderate	+	–	–	17	1
RCa-9	Q/ CYPA	moderate	–	–	–	17	1
RQm8	Q/CYPA	moderate	+	–	–	17	1
Group 3 (vaccine 2 wks prior, followed by low-dose repeated challenges)
RBr-9	Q/CYPA	moderate	+	–	+	1	0
REd-10	TFP/ TFP	restrictive	+	–	–	1	0
RQy-9	Q/ CYPA	moderate	–	–	–	1	0
RZi-7	Q/TRIM Q	high	–	–	–	1	0
Group 4 (low-dose controls for low dose repeated challenges)
REf-7	TFP/ TFP	restrictive	+	–	–	17	1
REy-6	TFP/ TFP	restrictive	–	–	–	4	0
RFz-6	TFP/ TFP	restrictive	–	–	–	2	0
RHt-9	TFP/ TFP	restrictive	+	–	–	17	1
RMg-10	Q/CYPA	moderate	+	–	–	1	0
Group 5 (vaccine 8 yrs prior, followed by high-dose challenge)
N901	TFP/ TFP	restrictive	–	–	–	NA	1
RKh-6	TFP/ Q	moderate	–	–	–	NA	1
RPh-6	TFP/ TFP	restrictive	–	–	–	NA	1
RSB3	TFP/ CYPA	moderate	–	–	–	NA	1
Group 6 (high-dose controls for high dose challenge)
RBj-7	Q/ Q	high	–	–	–	NA	1
RCn-7	TFP/TFP	restrictive	–	–	+	NA	1
RDt-9	TFP/ TFP	restrictive	–	–	–	NA	1
RIr-7	TFP/ CYPA	moderate	–	–	–	NA	1
RYt-9	TFP/ TFP	restrictive	–	+	–	NA	1
Group 7 (vaccine only for 2 wks)
RAm-5	TFP/ TFP	restrictive	+	–	+	no	no
RMh-9	TFP/ Q	moderate	+	–	–	no	no
RRu-7	TFP/ Q	moderate	–	+	–	no	no