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. 2013 Sep 30;8(9):e75556. doi: 10.1371/journal.pone.0075556

Table 1. TRIM5α and MHC Genotypes.

RM # TRIM5α genotype Susceptibility to infection MHC genotypes
# SIVsmE660 challenges
A01 B08 B17 Low-dose High-dose
Group 1 (vaccine 8 yrs prior, followed by low-dose repeated challenge)
RJi-6 TFP/ Q moderate 17 1
ROI-3 TFP/ TFP restrictive 5 0
RQh-6 Q/ CYPA moderate 17 1
RUu-3 TFP/ TFP restrictive + 4 0
Group 2 (vaccine 15 mos prior, followed by low-dose repeated challenges)
RAn-8 Q/ Q high 6 0
RBm-8 TFP/ Q moderate + 17 1
RCa-9 Q/ CYPA moderate 17 1
RQm8 Q/CYPA moderate + 17 1
Group 3 (vaccine 2 wks prior, followed by low-dose repeated challenges)
RBr-9 Q/CYPA moderate + + 1 0
REd-10 TFP/ TFP restrictive + 1 0
RQy-9 Q/ CYPA moderate 1 0
RZi-7 Q/TRIM Q high 1 0
Group 4 (low-dose controls for low dose repeated challenges)
REf-7 TFP/ TFP restrictive + 17 1
REy-6 TFP/ TFP restrictive 4 0
RFz-6 TFP/ TFP restrictive 2 0
RHt-9 TFP/ TFP restrictive + 17 1
RMg-10 Q/CYPA moderate + 1 0
Group 5 (vaccine 8 yrs prior, followed by high-dose challenge)
N901 TFP/ TFP restrictive NA 1
RKh-6 TFP/ Q moderate NA 1
RPh-6 TFP/ TFP restrictive NA 1
RSB3 TFP/ CYPA moderate NA 1
Group 6 (high-dose controls for high dose challenge)
RBj-7 Q/ Q high NA 1
RCn-7 TFP/TFP restrictive + NA 1
RDt-9 TFP/ TFP restrictive NA 1
RIr-7 TFP/ CYPA moderate NA 1
RYt-9 TFP/ TFP restrictive + NA 1
Group 7 (vaccine only for 2 wks)
RAm-5 TFP/ TFP restrictive + + no no
RMh-9 TFP/ Q moderate + no no
RRu-7 TFP/ Q moderate + no no