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. 2013 Sep 30;8(9):e74440. doi: 10.1371/journal.pone.0074440

Table 2. Risk of gastric non-cardia cancer associated with serum ghrelin presented as either quintiles or continuous variable before and after adjustment for serum PG I/II ratio, H.pylori status and smoking.

Non-adjusted Adjusted
Cases Controls OR 95% CI P value OR 95% CI P value
n (%) n (%)
Ghrelin Quintiles (pg/ml)
5th: 960–1098 3 (4.2%) 14 (19.4%) 1.00 1.00
4th: 824–957 5 (6.9%) 15 (20.8%) 1.56 0.31–7.75 0.691 1.06 0.17–6.81 0.952
3rd: 708–818 10 (13.9%) 14 (19.4%) 3.33 0.75–14.76 0.113 2.65 0.49–14.35 0.257
2nd: 579–693 17 (25.0%) 15 (20.8%) 5.60 1.35–23.23 0.018 3.63 0.70–18.78 0.124
1st: 246–570 36 (50.0%) 14 (19.4%) 12.01 2.99–48.25 <0.001 6.58 1.26–34.46 0.026
Decreasing ghrelin as continuous variable (scaled to 159 pg/ml) 2.09 1.53–2.84 <0.001 1.81 1.25–2.64 0.002