. 2013 Sep 30;8(9):e74440. doi: 10.1371/journal.pone.0074440

Table 4. Risk of esophageal adenocarcinoma associated with serum ghrelin presented as either quintiles or continuous variable before and after adjustment for serum PG I/II ratio, H.pylori status and smoking.

			Non-adjusted			Adjusted
	Cases	Controls	OR	95% CI	P value	OR	95% CI	P value
	n (%)	n (%)
Ghrelin Quintiles (pg/ml)
5^th: 995–1208	10 (27.8%)	7 (19.4%)	1.00			1.00
4^th: 904–992	9 (25.0%)	7 (19.4%)	0.90	0.23–3.58	0.881	0.31	0.05–1.76	0.185
3^rd: 789–889	9 (25.0%)	8 (22.2%)	0.79	0.20–3.06	0.730	0.72	0.14–3.81	0.697
2^nd: 631–783	6 (16.7%)	7 (19.4%)	0.60	0.14–2.58	0.492	0.41	0.06–2.67	0.352
1^st: 306–617	2 (5.6%)	7 (19.4%)	0.20	0.03–1.27	0.087	0.11	0.01–1.15	0.066
Decreasing ghrelin as continuous variable (scaled to 161 pg/ml)			0.65	0.43–1.01	0.053	0.60	0.35–1.04	0.068