Figure 5. Tumor-derived cfDNA detection in the plasma of animal 49.
Panel A: Agarose gel image of the breakpoint specific and control amplicon PCR for the various specimens obtained from animal 49. The breakpoint specific amplicon was not detected in the PBMC DNA. Panel B: Digital PCR results; mutated DNA content is displayed as breakpoint amplicon in percent of control amplicon. Panel C: Tomographic image of the lung of animal 49, the circle indicates the metastatic lesion.