Table 1. Details of the 52 source lesions for cell cultures included in the study, correspondent surgical, and VPAC times of the specimens and percentage of viable cells in the primary cultures.
Tumor histology | Cell culture | |||||||
# | Organ | Surgical Time [hours (h), minutes (′)] | VPAC Time [hours (h), minutes (′)] | Histological Type | % Stroma | % Tumor Cells | % CellViability | Cell Population |
1 | Colon | 1h45′ | 3h45′ | ADC | 30 | 70 | 0.0% | / |
2 | Stomach | 2h15′ | 4h10′ | ADC | 20 | 80 | 0.0% | / |
3 | Lung | 1h20′ | 4h15′ | ADC | 40 | 60 | 95.3% | Spindle |
4 | Lung | 1h20′ | 4h30′ | ADC | 40 | 60 | 93,9% | Mixed |
5 | Stomach | 1h30′ | 4h45′ | ADC | 35 | 65 | 97,0% | Spindle |
6 | Colon | 1h10′ | 5h00′ | ADC | 15 | 85 | 100,0% | Mixed |
7 | Colon | 0h40′ | 5h25′ | ADC | 5 | 95 | 96,8% | Mixed |
8 | Colon | 1h15′ | 5h25′ | ADC | 30 | 70 | 92,2% | Mixed |
9 | Adrenal | 1h20′ | 5h25′ | ADENOMA | 10 | 90 | 86,1% | Spindle |
10 | Breast | 1h35′ | 20h40′ | ILC | 40 | 60 | 0,0% | / |
11 | Lung | 2h15′ | 21h20′ | SFT | 8 | 92 | 96,4% | Mixed |
12 | Breast | 0h45′ | 21h40′ | IC-NST | 25 | 75 | 93,6% | Mixed |
13 | Breast | 1h40′ | 21h43′ | IC-NST | 10 | 90 | 94,8% | Mixed |
14 | Breast | 0h20′ | 22h20′ | ILC | 8 | 92 | 98,8% | Mixed |
15 | Breast | 0h55′ | 22h20′ | IC-NST | 15 | 85 | 95,0% | Mixed |
16 | Colon | 1h10′ | 22h30′ | ADC | 30 | 70 | 92,2% | Spindle |
17 | Lung | 0h10′ | 22h35′ | ADC | 2 | 98 | 97,7% | Mixed |
18 | Lung | 1h20′ | 22h35′ | SC | 50 | 50 | 96,5% | Mixed |
19 | Colon | 1h20′ | 22h45′ | ADC | 40 | 60 | 93,5% | Spindle |
20 | Breast | 1h10′ | 23h10′ | IC-NST | 20 | 80 | 96,9% | Mixed |
21 | Breast | 0h11′ | 23h17′ | IC-NST | 50 | 50 | 96,6% | Mixed |
22 | Breast | 1h50′ | 23h20′ | IC-NST | 60 | 40 | 96,3% | Mixed |
23 | Breast | 0h25′ | 23h25′ | ILC | 50 | 50 | 96,1% | Mixed |
24 | Breast | 1h10′ | 23h46′ | IC-NST | 40 | 60 | 98,5% | Mixed |
25 | Breast | 0h05′ | 23h50′ | IC-NST | 30 | 70 | 95,9% | Mixed |
26 | Colon | 0h45′ | 23h50′ | ADC | 15 | 85 | 86,6% | Mixed |
27 | Breast | 1h10′ | 23h50′ | MC | 10 | 90 | 94,0% | Mixed |
28 | Breast | 1h20′ | 24h00′ | IC-NST | 55 | 45 | 84,0% | Spindle |
29 | Breast | 0h50′ | 24h10′ | IC-NST | 30 | 70 | 97,9% | Mixed |
30 | Breast | 0h25′ | 24h16′ | IC-NST | 10 | 90 | 99,3% | Mixed |
31 | Breast | 0h15′ | 24h30′ | IC-NST | 20 | 80 | 99,2% | Mixed |
32 | Breast | 1h10′ | 24h35′ | IC-NST | 65 | 35 | 0,0% | / |
33 | Breast | 0h40′ | 25h00′ | PDC | 30 | 70 | 96,5% | Mixed |
34 | Lung | 1h40′ | 25h00′ | ADC | 40 | 60 | 97,3% | Spindle |
35 | Breast | 0h50′ | 25h05′ | ILC | 40 | 60 | 96,7% | Mixed |
36 | Breast | 0h35′ | 25h20′ | IC-NST | 30 | 70 | 96,0% | Mixed |
37 | Colon | 1h45′ | 26h10′ | ADC | 40 | 60 | 98,6% | Spindle |
38 | Thyroid | 2h20′ | 26h40′ | HCC | 20 | 80 | 96,3% | Mixed |
39 | Colon | 1h45′ | 27h40′ | ADC | 25 | 75 | 90,7% | Spindle |
40 | Breast | 0h27′ | 28h20′ | ILC | 30 | 70 | 0,0% | / |
41 | Colon | 0h50′ | 29h00′ | ADC | 20 | 80 | 86,5% | Mixed |
42 | Colon | 1h25′ | 39h20′ | ADC | 20 | 80 | 0,0% | / |
43 | Breast | 0h50′ | 42h15′ | IC-NST | 40 | 60 | 89,0% | Mixed |
44 | Breast | 0h20′ | 43h05′ | ILC+IPC | 25 | 75 | 97,3% | Mixed |
45 | Breast | 1h00′ | 45h05′ | IC-NST | 80 | 20 | 98,9% | Spindle |
46 | Breast | 3h00′ | 45h50′ | IC-NST | 40 | 60 | 98,7% | Mixed |
47 | Breast | 0h40′ | 46h47′ | IC-NST | 20 | 80 | 96,3% | Mixed |
48 | Colon | 1h10′ | 70h15′ | ADC | 30 | 70 | 97,5% | Spindle |
49 | Breast | 2h25′ | 72h25′ | ILC | 20 | 80 | 95,5% | Mixed |
50 | Colon | 1h45′ | 73h45′ | ADC | 25 | 75 | 96,7% | Spindle |
51 | Adrenal | 3h45′ | 74h05′ | PHEO | 5 | 95 | 0,0% | / |
52 | Stomach | 1h30′ | 75h15′ | ADC | 52 | 48 | 0,0% | / |
Legend: ADC: adenocarcinoma; HCC: Hurtle cell carcinoma; IC-NST: invasive carcinoma of no special type; ILC: infiltrating lobular carcinoma; IPC: intracystic papillary carcinoma; MC: medullary carcinoma; PDC: poorly differentiated carcinoma; PHEO: pheochromocytoma; SFT: solitary fibrous tumor; SC: squamous carcinoma.