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Frequency of LOH in SNP and Microsatellite sites flanking Trp53 and Nf1 genes (on Chromosome 11) from solid tumors arising in WT and Nf1+/− mice. The percentage of tumors demonstrating intact heterozygosity (Intact), LOH of the B6-derived allele (LOH B6), or LOH of the Sv129-derived allele (LOH 129), are shown for A. pheochromocytomas, B. carcinomas, C. sarcomas, and D. solid tumors arising in wildtype mice (mixed histologies).
