Figure 3.
Analysis of SRC Ablation in the OFA. A–C, Distance traveled, center distance traveled to total distance traveled ratio, number of movements, and number of rears measured during the OFA in WT and SRC−/− genotypes in male and female littermate mice. A, SRC1−/− female mice have decreased center/total distance traveled. B, SRC2−/− female mice have increased total distance traveled, increased center/total distance ratio, and increased movements compared with WT littermates in the OFA. C, SRC3−/− female mice have decreased total distance traveled, decreased center to total distance ratio, and decreased movements and rearing behavior. Mean ± SEM; *, P < .05.