Table IV.
Allele and Genotype Frequencies of CYP3A5 and ABCB1 Variants in the Jordanian Population
| SNP | Allele frequency | Genotype frequency | Expected | ||||||
|---|---|---|---|---|---|---|---|---|---|
| wild-type | Variant | Homozygous wild-type | Heterozygous | Homozygous variant | Homozygous wild-type | Heterozygous | Homozygous variant | HWE p valuea | |
| ABCB1 C3435T | 0.61 | 0.39 | 0.36 | 0.45 | 0.19 | 0.34 | 0.49 | 0.17 | 0.47 |
| CYP3A5 A6986G | 0.13 | 0.87 | 0.08 | 0.14 | 0.78 | 0.02 | 0.26 | 0.72 | 0.0007 |
SNP single nucleotide polymorphism; HWE Hardy–Weinberg equilibrium
a P value based on the exact test for Hardy–Weinberg equilibrium