Table A2.

Interobserver variability of multilayer appearance

Onsite reader	Offsite reader 1	Offsite reader 2	Cases (N = 132)
No	No	No	87
No	No	Yes	2
No	Yes	No	3
No	Yes	Yes	0
Yes	No	No	6
Yes	No	Yes	5
Yes	Yes	No	6
Yes	Yes	Yes	23

Onsite vs. Offsite reader 1: κ = 0.73 (SE = 0.07, 95% CI, 0.60–0.86). Onsite vs. Offsite reader 2: κ = 0.71 (SE = 0.07, 95% CI, 0.57–0.84). Offsite reader 1 vs. Offsite reader 2: κ = 0.64 (SE = 0.08, 95% CI, 0.48–0.79). SE indicates standard error.