Table 2. Persistence of anti-HBs antibody response to month 58 in initially HBsAg seronegative subjects (ATP cohort).
Vaccine group |
Timing | N | Seroprotected (%) |
GMT (mIU/ml) |
95% CI | |
---|---|---|---|---|---|---|
RTS,S/ AS02 |
Pre | 121 | 35.5 | 5.3 | 3.6 | 7.8 |
Month 5.5* | 105 | 97.1 | 3159.8 | 2001.0 | 4989.6 | |
Month 9 | 99 | 89.9 | 570.0 | 351.8 | 923.9 | |
Month 19** | 47 | 100 | 11737.2 | 6284.5 | 21921.0 | |
Month 35 | 48 | 89.6 | 393.4 | 204.8 | 755.9 | |
Month 46 | 52 | 90.4 | 253.9 | 136.0 | 473.9 | |
Month 58 | 39 | 79.5 | 105.5 | 50.3 | 221.1 | |
Rabies | Pre | 119 | 26.1 | 4.4 | 3.0 | 6.4 |
Month 5.5* | 101 | 35.6 | 6.1 | 4.1 | 9.2 | |
Month 9 | 89 | 39.3 | 7.5 | 4.7 | 11.8 | |
Month 19** | 51 | 52.9 | 11.6 | 6.7 | 20.1 | |
Month 35 | 51 | 54.9 | 12.5 | 7.4 | 21.0 | |
Month 46 | 54 | 40.7 | 8.1 | 4.8 | 13.8 | |
Month 58 | 51 | 39.2 | 7.6 | 4.5 | 12.8 |
Month 5.5 corresponds to post primary course
Month 19 corresponds to post booster. Seroprotection: subjects with anti-HBs titres ≥10 mIU/ml. GMT: geometric mean anti-HBs titres. 95% CI = 95% confidence intervals.