Table 1.
Demographic and clinical data.
| Patients with MDD (n = 21) | Healthy controls (n = 20) | p-Value | |
|---|---|---|---|
| Gender (female) | 11 | 11 | >0.05 |
| Age (years) | 51.0 (15.0) | 49.6 (13.9) | >0.05 |
| Education (years) | 14.3 (2.1) | 15.2 (2.0) | >0.05 |
| BDI | 25.3 (7.1) | 0.3 (1.2) | <0.01 |
| HDRS | 23.8 (7.9) | 0.5 (1.0) | <0.01 |
| GAF | 46.7 (11.3) | 100 (0) | <0.01 |
| Duration of MDD (years) | 14.7 (10.9) | – | – |
| Age of onset | 35.0 (13.6) | – | – |
| Number episodes | 5.0 (2.5) | – | – |
| Duration of current episode (weeks) | 16.2 (6.6) | – | |
| Anti-depressive medication (mono-/bi-/triple therapy) | 5/10/5 | 0/0/0 | – |
| Psychiatric co-morbidity (axis I) | 8 | 0 | – |
MDD, Major depression disorder; BDI, Beck depression inventory; HDRS, Hamilton depression rating scale; GAF, Global Assessment of Functioning Scale; group comparisons: χ2 (gender), two-sample t-test (age, education, BDI, HDRS, GAF).