Table 2.
Classification | Or7a | Or10a | Or22a | Or47a | Or49b | Or59b | Or85a | Or85b | Or98a | Total |
---|---|---|---|---|---|---|---|---|---|---|
Ligands (%) | 88 | 31 | 86 | 39 | 27 | 91 | 92 | 87 | 100 | 71 |
Agonists (>50 spikes/s) (%) | 63 | 31 | 81 | 33 | 18 | 64 | 69 | 70 | 92 | 58 |
Agonists (>100 spikes/s) (%) | 31 | 13 | 62 | 11 | 9 | 45 | 48 | 48 | 67 | 37 |
Inverse agonists (%) | 25 | 0 | 5 | 6 | 9 | 25 | 23 | 17 | 8 | 13 |
Summary of prediction accuracy percentages obtained by electrophysiology validation. Ligands = Agonists (≥50 spikes/s) + Inverse agonists (>50% reduction from baseline activity).