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Proportion of samples demonstrating injury with increasing spatial peak pulse averaged intensity at therapeutic and supratherapeutic levels. The large black arrow denotes the intensity at maximum clinical settings for stone propulsion with the current device, well below the dose-dependent injury threshold of >16,620 W/cm2 (dotted line). Gray arrows denote average intensity of shock wave lithotripsy (20,000 W/cm2) and diagnostic ultrasound (200 W/cm2) for reference.
