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A structure-switching biosensing system comprised of the bifunctional aptamer that can bind either ligands L1 or L2 and a deoxyribozyme with horseradish peroxidase-like activity (D) [75]. The binding of either L1 or L2 results in the liberation of the deoxyribozyme, allowing it to oxidize ABTS2- to produce the red-coloured ABTS-.
