FIG. 4.

RNA transcription levels (means±standard deviation [SD]) of 41 B. burgdorferi genes in ventricular muscle of C3H mice relative to gene transcription levels in C3H-scid mice during early and late infection. Samples from C3H mice were normalized to samples from C3H-scid mice, expressed in comparison to a reference gene (16S rRNA), and plotted as fold changes for each gene. Bars to the left of the center line indicate reduced relative expression and bars to the right indicate increased relative expression in C3H mice compared to C3H-scid mice. Zero relative expression indicates no expression in C3H mice. Transcriptional activity was not detected for crasp1 in C3H or C3H-scid mice during early or late infection, and was therefore not plotted.