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. 2013 Oct 2;33(40):15669–15674. doi: 10.1523/JNEUROSCI.2588-13.2013

Figure 3.

Figure 3.

Decreases in AMPAR-mediated excitation are specific to TA-CA1 synapses and correlated with affective state. a, Mean AMPA/NMDA ratios for SC-CA1 and TA-CA1 fEPSPs in slices from control and CUS rats (synapse–group interaction, F(1,8) = 7.525, p = 0.025). There was no difference between control and CUS at SC-CA1 synapses, whereas the ratio for TA-CA1 responses was significantly different for both CUS SC-CA1 and control TA-CA1 responses. b, Sucrose preference before and after 3 weeks in control and CUS rats. The difference was significant for CUS (2 × 2 repeated-measures ANOVA group–time interaction, F(1,21) = 23.33, p = 0.0001; CUS at 3 weeks, *p < 0.05 vs all other groups, Bonferroni test). c, AMPA/NMDAR ratios for TA-CA1 and SC-CA1 responses in each slice studied are plotted against the sucrose preference of the rat from which the slices were taken. TA-CA1 responses were correlated with sucrose preference (R2 = 0.36, p = 0.025), whereas SC-CA1 responses were not (R2 = 0.003, p = 0.43).