Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2013 Oct 2;33(40):15767–15778. doi: 10.1523/JNEUROSCI.1175-13.2013

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

Copyright © 2013 the authors 0270-6474/13/3315767-12$15.00/0

PMC Copyright notice

Figure 3. — The Shank3 regulation of NMDAR currents is influenced by agents that affect actin dynamics. A, Representative NMDAR currents in cultured cortical neurons transfected with control siRNA or Shank3 siRNA (DIV 19–22) in the presence of actin stabilizer phalloidin (1 μm), actin destabilizer latrunculin B (5 μm), or the microtubule stabilizer taxol (10 μm). Calibration: 200 pA, 0.5 s. B, Bar graph summary of NMDAR current density in control siRNA- or Shank3 siRNA-transfected neurons in the absence or presence of various cytoskeleton modifying agents. *p < 0.01, ANOVA.