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. Author manuscript; available in PMC: 2014 Nov 1.
Published in final edited form as: Int J Radiat Oncol Biol Phys. 2013 Nov 1;87(3):619–625. doi: 10.1016/j.ijrobp.2013.06.2063

Figure 4. Sodium-selenite supplementation suppresses radiation-induced increase in SEPP1 mRNA levels and toxicity.

Figure 4

NHFs were treated with 0–100 nM of sodium-selenite for 24 h prior to radiation: (A) Q-RT-PCR analysis of SEPP1 mRNA levels in 8 Gy irradiated NHFs at 48 h post-irradiation; (B) percentage of PI-positive (nonviable) cells in 4 Gy irradiated NHFs at 10 d post-irradiation; (C) a clonogenic assay was used to measure survival in 2 Gy irradiated NHFs. Error bars represent standard deviation of the mean; $ represents statistical significance relative to untreated, irradiated cells; p<0.05 as determined by a one-tailed students t-test; n=3.