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. 2013 Oct 1;4:288. doi: 10.3389/fmicb.2013.00288

FIGURE 3.

FIGURE 3

Minimum inhibitory concentrations to ciprofloxacin, ceftriaxone, and azithromycin in Shigella isolates from children with gastroenteritis at a state referral hospital inYucatan, Mexico, 2005–2011. Thick black lines indicate breakpoints for resistance. Number of isolates for each period was as follows: 2005–2006, n = 73; 2007–2009, n = 79 and 2010–2011, n = 66. (A) Ciprofloxacin MICs. Isolates were fully susceptible to ciprofloxacin throughout the study. Two isolates had ciprofloxacin MICs ≥ 0.12 μg/ml, only one of which was resistant to nalidixic acid. CLSI breakpoints for susceptibility and resistance are 1 and 4 μg/ml, respectively. (B) Ceftriaxone MICs. All isolates remained fully susceptible to ceftriaxone with no changes over the study period. CLSI breakpoints for susceptibility and resistance are 1 and 4 μg/ml, respectively. (C) Azithromycin MICs. Suggested breakpoints are the same as those proposed for Salmonella. Although isolates were apparently susceptible to azithromycin throughout the study period, 7–17% of these had an MIC = 16.