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. 2013 Sep 17;2013:160859. doi: 10.1155/2013/160859

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Copyright © 2013 Di Meng et al.

This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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Adoptive transfer of CD4⁺CD25⁺ Tregs reduces the vaccine efficacy under TN conditions. 10⁶ CD4⁺CD25⁺ Tregs from CHS+Ag group and TN+Ag group were adoptively transferred into TN+Ag mice on day 21 in conjunction with a 50 PFU H5N1 virus challenge. The mortalities of the two transferred groups (n = 6) were observed for 14 days.