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Histological alterations in the kidneys 120 h after administration of cisplatin (H&E staining, 100×). (A) Photomicrograph of a kidney in the control group. (B, C, D) Photomicrographs of kidneys after administration of cisplatin at 10, 25 and 50 mg/kg, respectively. The black arrow indicates proteinaceous casts in tubular lumen. The red arrow indicates tubular necrosis. G = glomerulus.
