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AEP specific TDP-43 cleavage sites determined in vitro
| Sequence | Trypticity | Position | Site |
|---|---|---|---|
| N.LVYVVNYPK.D | Semi | 71–79 | N70 |
| R.LVEGILHAPDAGWGNLVYVVN.Y | Semi | 56–76 | N76 |
| N.PGGFGNQGGFGNSR.G | Semi | 280–293 | N279 |
| R.FGGNPGGFGNQGGFGN.S | Semi | 276–291 | N291 |
| R.FGGNPGGFGN.Q | Semi | 276–285 | N285 |
| R.GGGAGLGNNQGSN.M | Semi | 294–306 | N306 |
| R.EPNQAFGSGNN.S | Semi | 362–372 | N372 |
