Table 3.

Multivariate Analysis for the Risk Factors of Disease-Specific Mortality in Classical and Follicular Variant of Papillary Thyroid Carcinoma and in Follicular Thyroid Carcinoma

	HR [CI]
Risk factors	C-PTC	FV-PTC	FTC
Age >45years	23.2 [14.5–36.9]*	17.6 [7.1–43.5]*	8.0 [4.0–16.0]*
Male sex	1.2 [0.9–1.5]	1.4 [0.9–2.1]	0.9 [0.6–1.4]
Tumor size >3.0 cm	3.1 [2.5–3.9]*	3.7 [2.4–5.9]*	2.4 [1.4–4.0]*
Extrathyroidal extension	4.4 [3.4–5.7]*	8.1 [5.1–13.1]*	3.8 [2.5–5.9]*
Lymph node metastases	2.5 [2.0–3.1]*	1.8 [1.2–2.8]*	5.8 [3.3–10.3]*
Distant metastases	3.8 [2.0–7.2]*	5.4 [2.1–13.8]*	7.5 [3.8–14.7]*
Total thyroidectomy	0.6 [0.4–0.8]*	0.8 [0.4–1.4]	1.1 [0.7–1.7]
Radioactive iodine	0.7 [0.5–0.8]*	0.9 [0.6–1.4]	0.7 [0.4–1.0]

p Values were obtained by Cox proportional hazards model; ^*p<0.05.

HR, hazard ratio; CI, confidence interval.