Fig. 5.

Example of a large and diverse superfamily with large coverage of protein-protein interfaces. This is the NAD(P)-binding Rossmann superfamily (CATH code.40.50.720). The Rossmann domain is always displayed in grey cartoon and shown in the same orientation. Extra-domains from the same chain are displayed as grey traces. Interacting partners are displayed as coloured traces. Interface residues on the Rossmann domain are coloured black. Fig. 5a through to 5e display PDB entries 1a7a, 1e3w, 1tt5, 1zud, and 2z1m, respectively. Fig. 5f shows the representative with residues coloured according to the same colour scheme as described at Fig. 3.