Fig. 4.

A, B) High SAA and SAP plasma levels in AKU patients. SAA (A) and SAP (B) plasma levels related with age and disease severity, thus reflecting also the progressive nature of AA amyloidosis. Experiments were performed in triplicate; data are presented as average values ± standard deviation. C) Congo Red staining of AKU subcutaneous periumbelical fat and AKU salivary gland tissues. Examples of CR fat smears and labial salivary gland biopsy of AKU Patients 3 and 5, under normal and in polarized light. CR staining confirmed the presence of amyloid deposition. Magnification 20 ×, a,b 10 ×. Representative images from a triplicate set are shown.