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. 2013 Oct;142(4):413–423. doi: 10.1085/jgp.201310971

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© 2013 Mamidi and Chandra

This article is distributed under the terms of an Attribution–Noncommercial–Share Alike–No Mirror Sites license for the first six months after the publication date (see http://www.rupress.org/terms). After six months it is available under a Creative Commons License (Attribution–Noncommercial–Share Alike 3.0 Unported license, as described at http://creativecommons.org/licenses/by-nc-sa/3.0/).

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Figure 6. — Effect of RcTnT_1–43Δ and RcTnT_44–73Δ on E_R in α- or β-MHC fibers. E_R was measured at pCa 4.3 as described previously (Ford et al., 2010). E_R represents the magnitude of the sudden stretch–mediated increase in the recruitment of additional force-bearing XBs (see the supplemental text for a detailed description). (A) E_R in fibers containing α-MHC. (B) E_R in fibers containing β-MHC. RcTnT_1–43Δ decreased E_R by ∼36% in α-MHC fibers, an effect that was counteracted in β-MHC fibers. Number of determinations was at least 10 for each group. Values are reported as mean ± SEM. **, P < 0.01.