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. 2012 Nov 5;32(38):4519–4528. doi: 10.1038/onc.2012.474

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Copyright © 2013 Macmillan Publishers Limited

This work is licensed under the Creative Commons Attribution-NonCommercial-No Derivative Works 3.0 Unported License. To view a copy of this license, visit http://creativecommons.org/licenses/by-nc-nd/3.0/

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Dot plots of Cav1 promoter methylation in human breast tumors. As Cav1 CGI shore methylation extends into part of the CpG island (CGI), the 5′-CGI shore analyzed here covers 500 bp upstream of CGI and 250 bp in the 5′ CGI. The 3′-CGI shore covers 500 bp downstream of CGI and 250 bp in the 3′ CGI. The CGI covers the center 1.5 kb CGI region. The black lines indicate medium (middle) and interquartile range (two ends). Two-sided Mann–Whitney test was used to analyze statistic significance and P-values are as indicated.