Table 5– Most common on-treatment adverse events (≥3% incidence in any treatment group).

	Placebo	Salmeterol	GSK961081
			Twice daily			Once daily
			100 μg	200 μg	400 μg	100 μg	400 μg	800 μg
Subjects	81	47	52	50	54	50	50	52
Any adverse event	20 (25)	8 (17)	12 (23)	12 (24)	16 (30)	16 (32)	15 (30)	13 (25)
Headache	5 (6)	2 (4)	2 (4)		5 (9)	5 (10)	5 (10)	2 (4)
Cough	2 (2)		2 (4)	4 (8)	1 (2)	5 (10)	5 (10)	4 (8)
Dysgeusia			2 (4)	3 (6)	3 (6)	2 (4)	1 (2)
Nasopharyngitis	3 (4)		1 (2)	3 (6)		3 (6)	1 (2)
Back pain	2 (2)		1 (2)				2 (4)
Dysphonia	2 (2)						1 (2)	2 (4)
Muscle spasms		1 (2)	1 (2)		2 (4)			1 (2)
Nausea	2 (2)					1 (2)	2 (4)
Myalgia	1 (1)	1 (2)					2 (4)
Palpitations		1 (2)			2 (4)

Data are presented as n or n (%).