Table 2.
Mean ± standard deviation values of spectral domain optical coherence tomography RNFL parameters with area under the receiver operating characteristics curves and sensitivities at fixed specificities for discriminating between preperimetric glaucoma and control groups
Parameter | Glaucoma (n=48) | Control (n=86) | P Value* | AUC (SE) | Sensitivity (Specificity = 80%) | Sensitivity (Specificity = 95%) |
---|---|---|---|---|---|---|
Temporal superior thickness | 102.0 ± 3.3 | 128.8 ± 2.0 | < 0.001 | 0.88 (0.03) | 80.2% | 47.6% |
Global thickness | 78.2 ± 2.0 | 92.8 ± 1.2 | < 0.001 | 0.86 (0.03) | 73.2% | 25.5% |
Temporal inferior thickness | 109.2 ± 4.0 | 136.3 ± 2.1 | < 0.001 | 0.81 (0.04) | 53.4% | 33.7% |
Nasal superior thickness | 79.3 ± 3.6 | 93.0 ± 2.2 | < 0.001 | 0.73 (0.05) | 34.8% | 15.1% |
Nasal thickness | 59.7 ± 2.6 | 69.6 ± 1.5 | < 0.001 | 0.70 (0.05) | 38.3% | 15.1% |
Nasal inferior thickness | 88.1 ± 4.3 | 106.0 ± 3.2 | < 0.001 | 0.68 (0.04) | 37.2% | 25.5% |
Temporal thickness | 63.2 ± 2.8 | 69.0 ± 1.5 | 0.04 | 0.62 (0.05) | 27.9% | 15.1% |
RNFL = retinal nerve fiber layer
AUC = area under the receiver operating characteristic curve
SE = standard error
For comparison of mean values of spectral domain optical coherence tomography parameters between glaucomatous and control eyes