Figure 1.

Relationship between aqueous diffusion coefficients at 37°C and molecular weights of the permeants. Diffusion coefficients were calculated by $D=\frac{k_{\mathrm{B}}T}{6\pi \eta r},$, where k_B is the Boltzmann constant, T is the absolute temperature, η is the viscosity of water at 37°C, and r is the average hydrodynamic radius of the permeant at 25°C assuming the radius does not change with temperature. Symbols: closed square, bevacizumab; closed triangle, ranibizumab; closed circle, FITC-BSA; open circle, FITC-ficoll 70 kDa; open diamonds, FITC-dextrans 20, 40, and 150 kDa. Data represent the mean and standard deviation for each permeant.