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. Author manuscript; available in PMC: 2014 Mar 1.
Published in final edited form as: J Pharm Sci. 2012 Dec 4;102(3):892–903. doi: 10.1002/jps.23387

Table 2.

Scleral Partition Coefficients for the Permeants

Mean ± SDa Range
Bevacizumab 0.31 ± 0.14 0.08–0.49
Ranibizumab 0.31 ± 0.10 0.10–0.43
FITC-BSAb 0.25–1.67
FITC-ficoll 70 kDa 0.39 ± 0.05 0.32–0.43
FITC-dextran 20 kDa 0.34 ± 0.08 0.28–0.45
FITC-dextran 40 kDa 0.32 ± 0.06 0.27–0.41
FITC-dextran 150 kDa 0.44 ± 0.09 0.29–0.61
a

Data represent the mean and standard deviation of at least four sclera samples for each permeant.

b

Concentration-dependent uptake was observed for FITC-BSA, and the mean value was not calculated.