Figure 1.

Proband with neuroendocrine cell hyperplasia of infancy (NEHI). Chest CT scan and lung biopsy specimen from infancy. A-C, Chest CT scan performed at age 7 months shows relatively diffuse ground-glass opacities, with some central prominence in the upper lobes. D-F, Specimen from a lung biopsy performed at age 7 months shows near normal architecture with mild peribronchiolar lymphocytic aggregates (D, hematoxylin and eosin [H&E], original magnification ×10; E, original magnification ×20). F, Bombesin immunostaining (original magnification ×20) demonstrates increased neuroendocrine cells within a bronchiole.