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Treatment algorithm for SSc-PAH used in the Johns Hopkins pulmonary hypertension program. 6MWT = 6-min walk test; ERA = endothelin receptor antagonist; FC = functional class; NT-proBNP = N-terminal pro-brain natriuretic peptide; PDE-5I = phosphodiesterase-5 inhibitor; RHC = right-sided heart catheterization; SQ = subcutaneous; SSc-PAH = systemic sclerosis-associated pulmonary arterial hypertension; WHO = World Health Organization.
