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. Author manuscript; available in PMC: 2014 Aug 28.
Published in final edited form as: J Am Chem Soc. 2013 Aug 15;135(34):12707–12721. doi: 10.1021/ja4049493

Figure 2. SPECT/CT imaging of the 111In/177Lu-octapa-trastuzumab and 111In/177Lu- DOTA-trastuzumab immunoconjugates.

Figure 2

Imaging studies in female nude athymic mice with subcutaneous SKOV-3 xenografts (identified by arrow at right shoulder, tumor volume ~ 100–150 mm3), showing transverse (top) and coronal (bottom) planar images bisecting the tumor, imaged at 24, 48, 72, 96, and 120 h post injection, see Figures S17–20 for 48 and 96 h time points.