Table 1.
Antiviral effect of different compounds on influenza viruses in MDCK cells.
| Compound | IC50 (nM)a |
|||||
|---|---|---|---|---|---|---|
| A/PR/8/34 (H1N1) | A/Aichi/2/68 (H3N2) | A/San Diego/1/2009 (H1N1 pdm09) | A/San Diego/21/2008 (H1N1) | A/San Diego/61/2008 (H1N1) | B/Taiwan/2/62 | |
| Diphyllin | 489.1 ± 14.32 | 38.32 ± 0.51 | 632.2 ± 3.67 | 372.8 ± 8.17 | 123.6 ± 2.98 | 139.8 ± 14.68 |
| Amantadine | >22,000 | 6.14 ± 0.45 | NTb | NTb | NTb | NTb |
| Oseltamivir | NTb | NTb | NTb | >40,000 | NTb | NTb |
a
IC50: the concentration of compound showed 50% inhibition of virus-induced cell cytopathic effect (mean ± SD).
b
NT: not tested.