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. Author manuscript; available in PMC: 2013 Oct 1.
Published in final edited form as: Biometrics. 2013 Jul 17;69(3):732–740. doi: 10.1111/biom.12064

Table 3.

Coefficient estimates for the average effect of time of ARV regimen change on outcome for n = 182 participants who experience virological failure on an efavirenz-containing regimen. Time is modeled in weeks and centered at M = 10 weeks.

Dose HIV-1 RNA Days below LOD CD4
Model Est. SE Est. SE Est. SE
Linear
β0 2.7093 0.0809 0.4878 0.0233 2.4376 0.0356
β1 0.0237 0.0102 −0.0071 0.0029 −0.0041 0.0038
Quadratic
β0 2.9102 0.1446 0.4131 0.0462 2.3421 0.091
β1 0.0244 0.0080 −0.0073 0.0027 −0.0045 0.0037
β2 −0.0035 0.0019 0.0013 0.0006 0.0016 0.0011

NOTE: Abbreviations used: limit of detection (LOD), coefficient estimate (Est.), standard error estimate (SE).