Skip to main content
. Author manuscript; available in PMC: 2014 Nov 1.
Published in final edited form as: Neurotox Res. 2013 Jul 4;24(4):549–559. doi: 10.1007/s12640-013-9410-7

Fig 2.

Fig 2

Deletion of EP1 receptor increases brain injury volume, cell death, and reduced cell survival. (A) Representative photomicrograph showing brain sections from EP1−/− and WT mice subjected to ICH injury. Quantification showed significantly larger brain injury volume in EP1−/− compared to WT mice at 72 h after ICH injury (P<0.01; n=6). (B) Fluoro-Jade B staining photomicrograph and quantification showed a significant increase in degenerating neurons in EP1−/− compared to WT mice following 72 h ICH (P<0.02; n = 4). (C) Representative image and quantitative analysis of the surviving neurons with Cresyl Violet staining showed significantly more surviving neurons in the peri-hematoma region of WT compared to the EP1−/− mice at 72 h post ICH (P<0.001; n=4). Values are expressed as mean ± S.D.