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. 2013 Oct 1;8(10):e76259. doi: 10.1371/journal.pone.0076259

Table 1. TCDD treatment decreased body weight and lymph node cell numbers 26 days after L. major infection.

TCDD Treatment
Vehicle 160 µg/Kg p
Body weight change (g) 2.23 ± 0.64 -0.23 ± 0.32 0.03
Thymus/Body weight (mg/g) 2.11 ± 0.36 0.91 ± 0.07 0.03
Total lymph node cells (x 10-6) 108.6 ± 21.4 5.3 ± 0.8 0.001
Percent CD4+ 28.3 ± 2.3 18.7 ± 3.8
Percent CD4+CD25+ 12.3 ± 0.9 23.0 ± 3.2 0.03
Percent CD8+ 13.0 ± 1.0 9.7 ± 1.9
Percent CD45R+ 54.7 ± 2.3 58.0 ± 3.5

Female wild type BALB/c mice were treated with peanut oil (vehicle) or TCDD (160 µg/Kg per os) one day prior to infection with one million stationary phase L. major promastigotes in one rear footpad. Data represent mean ± SEM for three animals per treatment group.