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The parameter estimates determined by nonlinear regression fit of the compartmental model to the Taxotere and Procet 8 data. Refer to Figure 8 for a description of the parameters.
| Parameter | Value | CV% |
|---|---|---|
| VC (mL) | 760 | 21 |
| VP (mL) | 5811 | 19 |
| CLD (mL/hour) | 2202 | 11 |
| CLHDTX (mL/hour) | 212 | 9 |
| Vmax (ng/hour) | 391464 | 38 |
| Km (ng/mL) | 124 | 59 |
| VPRO (mL) | 12 | 6 |
| KHYD (hour−1) | 0.076 | 7 |
