. Author manuscript; available in PMC: 2014 Dec 10.

Published in final edited form as: J Control Release. 2013 May 9;172(2):10.1016/j.jconrel.2013.04.025. doi: 10.1016/j.jconrel.2013.04.025

Table 3. Model simulation NCA pharmacokinetic parameters.

The pharmacokinetic parameters for the simulated data were estimated by noncompartmental analysis of the simulated Taxotere and Procet 8 DTX plasma profiles. See methods for abbreviations and calculations.

	lambda 1/h	t_1/2 h	C_max μg/mL	t_max h	AUC_inf μg × h/mL	V L/kg	CL L/h/kg

Procet 8- DTX	0.069	10	0.037	4	0.8	-	13
Taxotere-DTX	0.226	3	2.9	0	2	3.5	5