Table 6. Safety profiles of values and percentage changes from baseline after 12 weeks of treatment with pitavastatin or atorvastatin.
Baseline | Week 12 | Percentage change (%)# | Baseline vs. week 12 p-value | |
---|---|---|---|---|
hsCRP [mg/dL] | ||||
PTV | 0.17 ± 0.2 | 0.14 ± 0.21 | −28.6 ± 157.4 | 0.08 |
ATV | 0.33 ± 1.1 | 0.19 ± 0.38 | −10.8 ± 124.9 | 0.38 |
CPK [U/L] | ||||
PTV | 125.4 ± 64.6 | 153.2 ± 252.7 | 22.3 ± 140.6 | 0.13 |
ATV | 130.9 ± 81.1 | 142.7 ± 90.8 | 17.8 ± 45.8 | 0.0001 |
AST [U/L] | ||||
PTV | 27.5 ± 10.7 | 28.3 ± 13.6 | 5.9 ± 29.3 | 0.05 |
ATV | 26.8 ± 7.1 | 27.4 ± 8.5 | 4.5 ± 24.9 | 0.07 |
ALT [U/L] | ||||
PTV | 31.5 ± 17.9 | 32.1 ± 19.5 | 6.7 ± 33.8 | 0.06 |
ATV | 30.6 ± 15.1 | 31.1 ± 14.3 | 10.5 ± 39.9 | 0.008 |
Gamma GT [U/L] | ||||
PTV | 37.6 ± 37 | 34.8 ± 25.6 | −5.6 ± 29.9 | 0.07 |
ATV | 36.8 ± 27.5 | 37. ± 27.1 | 6.2 ± 32.3 | 0.05 |
Total bilirubin [mg/dL]** | ||||
PTV | 0.8 ± 0.3 | 0.7 ± 0.3 | −0.9 ± 31.8 | 0.77 |
ATV | 0.8 ± 0.3 | 0.9 ± 0.4 | 14.0 ± 43.0 | 0.001 |
BUN [mg/dL] | ||||
PTV | 15.7 ± 3.6 | 16.4 ± 4.0 | 5.2 ± 22.0 | 0.02 |
ATV | 15.7 ± 3.9 | 16.1 ± 4.5 | 4.2 ± 19.8 | 0.03 |
Serum creatinine [mg/dL] | ||||
PTV | 0.8 ± 0.2 | 0.8 ± 0.2 | −1.2 ± 9.9 | 0.24 |
ATV | 0.8 ± 0.2 | 0.8 ± 0.2 | −0.7 ± 10.7 | 0.54 |
LDH [U/L] | ||||
PTV | 192.0 ± 31.7 | 189.7 ± 33.8 | −0.3 ± 14.6 | 0.84 |
ATV | 193.8 ± 38.4 | 195.3 ± 47.7 | 1.3 ± 17.9 | 0.45 |